Introduction.The study of rheological properties (dynamic and plastic viscosity, yield strength, the degree and presence of a thixotropic effect, the nature of the type of flow) are important for the development of soft dosage forms.These properties affect the stability of the dosage form during storage, its technological and consumer characteristi
Background: Meningiomas are the most common benign central nervous system tumors.However, a sizeable fraction recurs, irrespective of histological grade.No molecular marker is available for prediction of recurrence in these tumors.Materials and Methods: We analyzed recurrent meningiomas with paired parent and recurrent tumors by fluorescence in sit
Y chromosomes across diverse species convergently evolve a gene-poor, heterochromatic organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA.Sexual antagonism and a loss of recombination play major roles in the Bottle Openers degeneration of young Y chromosomes.However, the processes shaping the evolution of mature, alr
Abstract Chimeric Games and Activities antigen receptor (CAR) NK and T cell therapy are promising immunotherapeutic approaches for the treatment of cancer.However, the efficacy of CAR NK/T cell therapy is often hindered by various factors, including the phenomenon of trogocytosis, which involves the bidirectional exchange of membrane fragments betw
Mycobacterium tuberculosis is an important global pathogen for which new drugs are urgently required.The ability of the organism to survive and multiply within macrophages may contribute to the lengthy treatment regimen with multiple drugs that are required to cure the infection.We screened the MyriaScreen II diversity library of 10,000 compounds t